Additional file 3: of The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype

Assessment of receptor negative cells for E2-mediated PR upregulation. Relative steady state levels of ERα, PR-A, PR-B, AR and the ERα regulated gene CTSD and PR regulated gene FKBP5 in the ERα and PR negative breast cancer cells BT-20, MDA-MB-231 and MDA-MB-453 treated for 16 h with ethanol (v.c.), 10nM DHT, 10nM P4 and 10nM E2. (XLS 760 kb)

针对雌二醇（E2）介导的孕激素受体（PR）上调效应开展的受体阴性细胞评估实验。本数据集检测了经乙醇（溶剂对照，v.c.）、10nM双氢睾酮（DHT）、10nM孕酮（P4）与10nM雌二醇（E2）处理16小时的雌激素受体α（ERα）与PR双阴性乳腺癌细胞BT-20、MDA-MB-231及MDA-MB-453中，ERα、PR-A、PR-B、雄激素受体（AR），以及ERα调控基因CTSD与PR调控基因FKBP5的相对稳态表达水平。（文件格式为XLS，大小760 kb）