Table 1_Effectiveness of tailored multichannel interventions on weight loss among adolescents: a randomized controlled trial.pdf

BackgroundSeveral weight loss interventions have been provided for adolescents. However, these interventions were often not adequately tailored to their perception. This study aims to investigate the effectiveness of tailored multichannel interventions on weight loss among adolescents.
MethodsThis study is a randomized controlled trial. A total of 279 adolescents, whose Body Mass Index (BMI) was≥25 kg/m2, were recruited in January 2025 from eight non-medical colleges at Mansoura University, Mansoura, Egypt. For the intervention group (IG; n = 133), an intervention was developed based on the Health Belief Model (HBM). The intervention has been designed and administered by a multidisciplinary team for 5 months, until June 2025, via in-person meetings, telephone calls, and digital messages. The control group (CG; n = 146) received basic education over two face-to-face sessions. The primary outcome is the mean difference in BMI. Secondary outcomes include self-administered HBM constructs. All outcomes were assessed at baseline (T0), 2 months (T1), and 5 months (T2).
ResultsThe independent t-test revealed statistically significant differences between the groups in the scores of the BMI at T2 (−1.75, 95% CI: −2.48 to −1.02, p < 0.001, Cohen’s d = −0.57). Additionally, two-way repeated measures ANOVA demonstrated a statistically significant interaction effect (Group × Time), F(1.24, 342.36) = 49.72, p = <0.001, partial η2 = 0.15, as well as statistically significant differences within-group, F(1.24, 342.36) = 29.73, p = <0.001, partial η2 = 0.10. Regarding HBM, the intervention produced statistically significant main effects between and within groups over time for perceived susceptibility, benefits, self-efficacy, and internal cues to action (all p < 0.05).
ConclusionAdolescents in the IG experienced significant weight loss and a positive change in their perception of weight management. The study findings suggest that such tailored multichannel interventions be integrated with other community-based participatory approaches to enhance external cues to action and overcome the perceived barriers in the long term.
Clinical trial registrationhttps://clinicaltrials.gov/study/NCT06767072, NCT06767072.

背景 目前已针对青少年群体开发了多款减重干预方案，但此类方案往往未能充分贴合青少年的主观认知与需求。本研究旨在探讨定制化多渠道干预措施对青少年减重的效果。
方法 本研究为随机对照试验。2025年1月，研究人员从埃及曼苏拉大学曼苏拉校区的8所非医学院校中招募了279名体重指数（Body Mass Index，BMI）≥25 kg/m²的青少年作为研究对象。其中干预组（IG；n=133）采用基于健康信念模型（Health Belief Model，HBM）开发的干预方案，该方案由多学科团队设计并实施，干预周期为5个月（至2025年6月），干预形式包括面对面交流、电话沟通与数字化讯息推送。对照组（CG；n=146）仅接受2次面对面授课形式的基础健康教育。本研究的主要结局指标为BMI的平均变化值，次要结局指标包括自评健康信念模型相关构念。所有结局指标均在基线（T0）、干预2个月（T1）及干预5个月（T2）时进行评估。
结果 独立样本t检验结果显示，在T2时点，两组受试者的BMI评分存在统计学显著性差异（−1.75，95%置信区间：−2.48~−1.02，p<0.001，科恩d值=−0.57）。此外，双向重复测量方差分析结果表明，组别与时间存在显著的交互效应（Group×Time）：F(1.24, 342.36)=49.72，p<0.001，偏η²=0.15；组内比较同样存在统计学显著性差异，F(1.24, 342.36)=29.73，p<0.001，偏η²=0.10。针对健康信念模型相关指标，干预措施在不同时点的组间与组内比较中，对感知易感性、感知益处、自我效能感及内部行动线索均产生了统计学意义显著的主效应（所有p<0.05）。
结论 干预组青少年实现了显著的体重下降，同时其体重管理相关认知也发生了积极改变。本研究结果提示，此类定制化多渠道干预方案可与其他社区参与式干预措施相结合，以强化外部行动线索，长期克服减重过程中的感知障碍。临床试验注册信息：https://clinicaltrials.gov/study/NCT06767072，注册号NCT06767072。