Error rates per kilobase, raw and corrected.

aReported average coverage of 2× assembly.bBased on observed differences between aligned 2× and ENCODE sequences. Note that, because estimates are based on >2Mb of aligned sequence in all cases and >10Mb in most cases (Table S2), the contribution of sampling error to the estimates shown here is negligible (standard errors are typically ≈0.01 per kb).cEstimate of polymorphism rate (based on highest quality bases).dCorrected error rate, equal to raw difference rate minus estimated polymorphism rate.eThe guinea pig is shown for comparison. The genome assembly reflects −7× coverage. The low estimated polymorphism rate may result from the use of the same inbred line in the 2× and ENCODE projects (unconfirmed).

a. 已报道的2×组装基因组平均测序覆盖度。
b. 基于比对得到的2×测序数据与ENCODE序列之间的观测差异计算所得。注：由于所有估算均基于超过2Mb的比对序列，且多数样本的比对序列长度超过10Mb（详见补充表S2），因此本研究展示的估算值中抽样误差的影响可忽略不计（标准误差通常约为每千碱基0.01）。
c. 多态性率估算值（基于最高质量的碱基序列）。
d. 校正后错误率，等于原始差异率减去估算得到的多态性率。
e. 本次分析以豚鼠作为参照样本。其基因组组装覆盖度为−7×，估算得到的多态性率偏低，可能是由于2×测序项目与ENCODE项目使用了同一近交系豚鼠（该结论尚未得到证实）。