Univariate Associations with Number of Acute Exacerbations and COPD-Related Hospitalizations.

6MWT denotes 6-minute walk test; SGRQ-AS St. George's Respiratory Questionnaire Activity Score; FEV1 forced expiratory volume in 1 second; AE acute exacerbation; SGRQ-TS St. George's Respiratory Questionnaire Total Score; MMRC Modified Medical Research Council; and ref reference group.§Rate ratios calculated for a MCID of 30 m [37] for 6MWT and 4 units [42] for SGRQ-AS. The regression coefficients (SE) in natural log risk per 30-m decrease in 6MWT predicting AEs and COPD-related hospitalizations are 0.0976 (0.0323) and 0.1946 (0.0516), respectively. The regression coefficients (SE) in natural log risk per 4-unit decrease in SGRQ-AS predicting AEs and COPD-related hospitalizations are 0.0712 (0.0206) and 0.1091 (0.0347), respectively.†N = 168.

6MWT指6分钟步行试验（6-minute walk test）；SGRQ-AS为圣乔治呼吸问卷活动评分（St. George's Respiratory Questionnaire Activity Score）；FEV1为一秒用力呼气容积（forced expiratory volume in 1 second）；AE为急性加重（acute exacerbation）；SGRQ-TS为圣乔治呼吸问卷总评分（St. George's Respiratory Questionnaire Total Score）；MMRC为改良医学研究委员会（Modified Medical Research Council）；ref为参照组（reference group）。§ 针对6MWT的最小临床重要差异（Minimal Clinically Important Difference，MCID）为30米[37]、SGRQ-AS为4个单位[42]，据此计算率比。针对6MWT每下降30米，预测AE与慢性阻塞性肺疾病（Chronic Obstructive Pulmonary Disease，COPD）相关住院的风险自然对数回归系数（标准误，Standard Error，SE）分别为0.0976（0.0323）与0.1946（0.0516）。针对SGRQ-AS每下降4个单位，预测AE与COPD相关住院的风险自然对数回归系数（标准误）分别为0.0712（0.0206）与0.1091（0.0347）。† 样本量N=168。