A Combination of Chemotherapy and Oncolytic Virotherapy Sensitizes Colorectal Adenocarcinoma to Immune Checkpoint Inhibitors in a cDC1-Dependent Manner

Comparison of transcriptome data in tumors from mice treated with combinations of mitomycin C, oncolytic HSV-1, anti-PD-1 and anti-CTLA-4. RNA was extracted from tumors and transcriptome data was assessed using a Clariom S assay.

本数据集针对经丝裂霉素C（mitomycin C）、溶瘤单纯疱疹病毒1型（oncolytic HSV-1）、抗PD-1（anti-PD-1）与抗CTLA-4（anti-CTLA-4）联合治疗的小鼠肿瘤组织的转录组数据开展对比分析。实验从肿瘤组织中提取RNA，并采用Clariom S检测（Clariom S assay）完成转录组数据的评估。