Visible-Light-Mediated Synthesis of Thio-Functionalized Pyrroles

An inimitable illustration of the
green-light-induced synthesis
of thio-functionalized pyrroles has been established using β-ketodinitriles
and thiophenols as the reacting partners and eosin Y as the photocatalyst.
Large-scale synthesis and some useful synthetic modifications of the
thio-functionalized pyrroles are also demonstrated.

本研究以β-酮二腈 (β-ketodinitriles) 与硫酚 (thiophenols) 为反应底物，以曙红Y (eosin Y) 作为光催化剂，确立了一套独特的硫官能化吡咯 (thio-functionalized pyrroles) 绿光诱导合成方法。此外，本研究还实现了该类硫官能化吡咯的大规模合成，并展示了若干实用的合成修饰策略。