The canonical pathways that were affected in nonagenarian males.

The pathways that were significant only in males are shown. The p-values were derived from Fisher’s exact test, −log(0.05) = 1.3 and the Benjamini-Hochberg-corrected t-test (FDR), −log(0.25) = 0.61. The ratio is the number of differentially expressed genes in the data set divided by the total number of genes in the given pathway.

仅在雄性样本中具有显著性的通路已在此展示。本次分析的p值来源于费希尔精确检验（Fisher’s exact test），其显著性临界值对应−log(0.05)=1.3；同时采用经本杰明尼-霍赫贝格校正的t检验（Benjamini-Hochberg-corrected t-test，FDR），该检验的显著性临界值对应−log(0.25)=0.61。此处的比值为数据集中差异表达基因的数量与给定通路内总基因数的比值。