Possible mechanism for molecular mimicry and examples from pathogens.
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Mimicry by transfer of nucleic acids or convergence of proteins can be identified in silico by comparative genomics (CRIT: Complement C2 receptor inhibitor trispanning (CRIT), C4BP: m7G, 7-methyl guanosine; CSP, circumsporozoite protein; Complement-binding protein, CR1: Complement receptor 1, FHL-1: factor-H-like protein-1, fH: factor H, MCP: Membrane cofactor protein, DAF: Decay-accelerating factor).
经由核酸转移或蛋白质趋同演化形成的模拟现象,可通过比较基因组学结合计算机模拟(in silico)分析进行鉴定。相关术语说明如下:补体C2受体三跨膜抑制剂(Complement C2 receptor inhibitor trispanning,缩写CRIT);C4BP对应的m7G即7-甲基鸟苷(7-methyl guanosine);环子孢子蛋白(circumsporozoite protein,缩写CSP);补体结合蛋白(Complement-binding protein);补体受体1(Complement receptor 1,缩写CR1);因子H样蛋白1(factor-H-like protein-1,缩写FHL-1);因子H(factor H,缩写fH);膜辅助蛋白(Membrane cofactor protein,缩写MCP);衰变加速因子(Decay-accelerating factor,缩写DAF)。
创建时间:
2015-12-02



