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Additional file 6: of Negative and positive control ranges in the bacterial reverse mutation test: JEMS/BMS collaborative study

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Figure S5. Dose-response curves of revertant Escherichia coli strain WP2uvrA colonies following treatment with AF-2 in the absence of S9 mix (a), or with 2AA in the presence of S9 mix (b). Individual dose-response curves were generated using results produced by each participating laboratory in 2016 (different colors indicate different laboratories). The doses tested were 0.0025, 0.005, and 0.01 μg/plate for AF-2, and 2.5, 5.0, and 10 μg/plate for 2AA. (ODP 342 kb)

补充图S5:无S9混合液(S9 mix)条件下经AF-2处理的回复突变大肠杆菌(Escherichia coli)WP2uvrA菌株菌落的剂量-反应曲线(a),以及添加S9混合液条件下经2AA处理的该菌株菌落的剂量-反应曲线(b)。所有单条剂量-反应曲线均基于2016年各参与实验室的实验结果绘制,不同颜色对应不同实验室。本次测试的剂量设置为:AF-2为0.0025、0.005及0.01 μg/平板,2AA为2.5、5.0及10 μg/平板。(ODP 342 kb)
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2018-04-04
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