RNA-seq analysis of subcutaneus inguinal adipose tissue from Tmem120a fat specific knockout mice (females)

Tmem120a was shown to be important for adipocytes differentiation. Here we analyze gene expression in suncutaneous adipose tissue form Tmem120a fat-specific knockout mouse on high fat vs low fat diet. Overall design: Wild type and kncokout female mice were subjected to low fat and high fat diet for 15 weeks. Tissues were collected at the age of 6 months and RNA extracted.

已有研究表明，Tmem120a对脂肪细胞分化具有重要调控作用。本研究针对高脂饮食与低脂饮食饲喂条件下的Tmem120a脂肪特异性敲除小鼠的皮下脂肪组织开展基因表达分析。实验设计：将野生型与Tmem120a敲除型雌性小鼠分别饲喂低脂饮食与高脂饮食，持续15周；于小鼠6月龄时采集组织样本并提取核糖核酸（RNA）。