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Additional file 10 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin

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Figshare2024-10-02 更新2026-04-08 收录
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Additional file 10: Table S2. Podocyte-specific sequencing data – statistical analyses. Differential expression between male & female vehicle groups. Differential expression between male & female rapamycin-treated groups. Log2FC (before & after shrinkage) and P-values for the rapamycin effect differential expression in each sex. The combined P-value represents minus the logarithm (base 10) of the product between male & female P-values. List of genes that had a statistically significant interaction of rapamycin treatment effect between the sexes.

补充文件10:附表S2。足细胞(Podocyte)特异性测序数据的统计分析。涵盖以下内容:赋形剂组雄性与雌性间的差异表达分析、雷帕霉素处理组雄性与雌性间的差异表达分析;各性别中雷帕霉素效应差异表达的log₂倍数变化(收缩校正前后,Log2FC)及P值;组合P值为雄性与雌性P值乘积的以10为底的负对数;以及存在性别间雷帕霉素处理效应具有统计学显著交互作用的基因列表。
提供机构:
Rinschen, Markus M.; Grahammer, Florian; Al-Diab, Ola; Beule, Dieter; Kusch, Angelika; Wang, Pinchao; Blanc, Eric; Ashraf, Muhammad Imtiaz; Catar, Rusan Ali; Huber, Tobias B.; Sünkel, Christin; Gürgen, Dennis; Zhao, Hongfan; Bachmann, Sebastian; Fritsche-Guenther, Raphaela; Kirwan, Jennifer A.; Rajewsky, Nikolaus
创建时间:
2024-10-02
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