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This platform will help in the deduction of evolutionary relationships among enzymes such as aminotransferases, nucleotidyltransferases, acetyltransferases and SDR family enzymes. It can also facilitate experimental studies such as direct enzyme assays to validate putative annotations, establish structure-function relationship, expression profiling to determine the function, determine the phenotypic consequences of gene knock-out/knock-in and complementation studies.

本平台可用于推演氨基转移酶(aminotransferases)、核苷酸转移酶(nucleotidyltransferases)、乙酰转移酶(acetyltransferases)以及SDR家族酶(SDR family enzymes)等酶类之间的演化关系。同时,该平台还可助力多项实验研究,涵盖用于验证推定注释的直接酶活测定、用于建立结构-功能关联的研究、用于明确功能的表达谱分析、用于确定基因敲除/敲入表型效应的实验,以及互补实验研究。

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