Sensation of electric fields in Drosophila melanogaster

Electrosensation has emerged as a crucial sensory modality for social communication, foraging, and predation across the animal kingdom. However, its presence and functional role as well as the neural basis of electric field perception in Drosophila and other invertebrates remain unclear. In environments with controlled electric fields, we identified electrosensation as a new sense in the Drosophila melanogaster larva. We found that the Drosophila larva performs robust electrotaxis: when exposed to a uniform electric field, larvae migrate toward the cathode (negative potential) and quickly respond to changes in the orientation of the field to maintain cathodal movement. Through a behavioral screen, we identified a subset of sensory neurons located at the tip of the larval head that are necessary for electrotaxis. Calcium imaging revealed that a pair of Gr66a-positive sensory neurons (one on each side of the head) encodes the strength and orientation of the electric field. Our results ind..., , , # Data from: Sensation of electric fields in Drosophila melanogaster

This repository contains all data that is used to run all the code found on [https://gitlab.com/davidtadres/electrotaxis_publication](https://gitlab.com/davidtadres/electrotaxis_publication) to create all figures presented in the paper titled 'Sensation of electric fields in Drosophila melanogaster'

## Description of the Data and file structure

Folder 'Behavior' contains all behavioral data, folder 'Ca_imaging_data' contains all data related to calcium imaging, folder 'simulation' contains all data related to simulations and folder 'IHC' contains all immunohistochemistry images.

We recommend to use this repository in the following order:

1. Identify the figure in the manuscript one wants to re-plot (e.g. Figure 1F)
2. download the repository containing all code using the files found here.
3. Follow the Readme of the repository to point the code to the data from datadryad
4. In the folder 'eletrotaxis_publication' ...,

电感受（electrosensation）已成为动物界中用于社会交流、觅食与捕食的关键感官模态。然而，果蝇（Drosophila）及其他无脊椎动物的电场感知的存在性、功能角色及其神经基础仍未明确。在可控电场环境中，我们在黑腹果蝇（Drosophila melanogaster）幼虫中发现了电感受这一新的感官形式。研究发现，果蝇幼虫表现出显著的趋电性（electrotaxis）：当处于均匀电场中时，幼虫会向阴极（负电位区域）迁移，并能快速响应电场方向的变化以维持向阴极的移动。通过行为筛选实验，我们鉴定出位于幼虫头部尖端的一类感觉神经元是趋电性行为所必需的。钙成像（calcium imaging）实验显示，一对Gr66a阳性的感觉神经元（头部两侧各一个）可编码电场的强度与方向。我们的研究结果表明……，，，# 数据来源：《黑腹果蝇的电场感知》

本仓库包含用于运行[https://gitlab.com/davidtadres/electrotaxis_publication](https://gitlab.com/davidtadres/electrotaxis_publication) 中所有代码的全部数据集，用于复现论文《黑腹果蝇的电场感知》中的所有图表。

## 数据与文件结构说明

'Behavior'文件夹存储所有行为学实验数据；'Ca_imaging_data'文件夹存储所有钙成像相关数据；'simulation'文件夹存储所有模拟实验相关数据；'IHC'（免疫组化Immunohistochemistry）文件夹存储所有免疫组化图像。

我们建议按照以下流程使用本仓库：
1. 确定需要复绘的论文插图（例如图1F）
2. 通过本仓库提供的文件下载包含全部代码的仓库
3. 按照代码仓库的README文件指引，将代码路径指向datadryad平台的数据集
4. 在'eletrotaxis_publication'文件夹中……，