High resolution TMPRSS2 structure following acylation by nafamostat

High resolution TMPRSS2 structure following acylation by nafamostat Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, ... Authors: Fraser, B.J, Dong, A, Kutera, M, Seitova, A, Li, Y, Hutchinson, A, Edwards, A, Benard, F, Levon, H, Arrowsmith, C. Deposit date: 2023-11-16 Release date: 2024-01-31 Last modified: 2026-01-14 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors. J.Med.Chem., 68, 2025经萘莫司他（nafamostat）酰化后的高分辨率跨膜丝氨酸蛋白酶2（TMPRSS2）结构 描述项：1,2-乙二醇、N-乙酰-β-D-葡萄糖胺-(1→4)-N-乙酰-β-D-葡萄糖胺-(1→4)-[α-L-岩藻吡喃糖-(1→6)]-N-乙酰-β-D-葡萄糖胺、4-脒基苯甲酸…… 作者：B.J.弗雷泽、A.董、M.库泰拉、A.塞托娃、Y.李、A.哈钦森、A.爱德华兹、F.贝纳尔、H.莱文、C.阿罗史密斯 提交日期：2023-11-16 发布日期：2024-01-31 最后修改日期：2026-01-14 测试方法：X射线衍射（分辨率1.58 Å） 引用文献：《小分子TMPRSS2抑制剂的大型分子库对接与生物物理分析》，《药物化学杂志》（J. Med. Chem.），第68卷，2025年