Lignin deconstruction by anaerobic fungi

Lankiewicz_Lignin_REgulated_GOI.xlsx - A table of high priority genes of interest from this study, determined by combining differential expression with lignin deconstruction observations and predictive modeling. Genes of interest for this study are those that meet our criteria of upregulation on all three lignocelluloses and possession of a signal peptide.

Lankiewicz_GOI_Neocallimastigomycetes_BLAST_Result.xlsx - Summary: A table of the identified, upregulated genes of highest interest for this study that are conserved across the Neocallimastigomycetes taxonomic class. These results demonstrate that homologs of many gene products of interest are present in every available, sequenced anaerobic fungal genome, and some of these predicted peptides are highly conserved.

Lankiewicz_Lignin_REgulated_GOI.xlsx - 该表格汇总了本研究筛选得到的高优先级目的基因（Gene of Interest, GOI），通过整合差异表达分析、木质素解构观测结果与预测建模方法确定。本研究的目的基因需满足两项筛选标准：在三种木质纤维素底物上均呈现上调表达，且携带信号肽。
Lankiewicz_GOI_Neocallimastigomycetes_BLAST_Result.xlsx - 该表格为本研究中鉴定得到的、在新美鞭菌纲（Neocallimastigomycetes）分类类群中保守的高优先级上调表达目的基因的汇总结果。分析结果表明，本研究涉及的多数目的基因产物的同源蛋白存在于所有已测序的厌氧真菌基因组中，其中部分预测肽段具有高度保守性。