Disordered Sleep and Myopia Risk among Chinese Children

PurposeDisordered sleep and myopia are increasingly prevalent among Chinese children. Similar pathways may be involved in regulation of both sleep cycles and eye growth. We therefore sought to examine the association between disordered sleep and myopia in this group.MethodsUrban primary school children participating in a clinical trial on myopia and outdoor activity underwent automated cycloplegic refraction with subjective refinement. Parents answered questions about children's sleep duration, sleep disorders (Children's Sleep Habits Questionnaire [CSHQ]), near work and time spent outdoors.ResultsAmong 1970 children, 1902 (96.5%, mean [standard deviation SD] age 9.80 [0.44] years, 53.1% boys) completed refraction and questionnaires. Myopia 41). In logistic regression models by eye, odds of myopia ConclusionsMyopia and disordered sleep were both common in this cohort, but we did not find consistent evidence for an association between the two.Trial Registrationclinicaltrials.gov NCT00848900

研究目的：睡眠紊乱与近视在我国儿童群体中的患病率均呈逐年上升趋势。睡眠周期调控与眼球生长发育可能共享相似的生物学通路。因此本研究旨在探讨该群体中睡眠紊乱与近视的相关性。
研究方法：本研究纳入参与近视与户外活动临床试验的城市小学儿童，对其实施自动睫状肌麻痹验光（automated cycloplegic refraction）并联合主观矫正。由家长填写调查问卷，内容涵盖儿童睡眠时长、睡眠紊乱情况（采用儿童睡眠习惯问卷[Children's Sleep Habits Questionnaire, CSHQ]）、近距离用眼时长及户外活动时长。
研究结果：本研究共纳入1970名儿童，其中1902名（占比96.5%，平均年龄9.80±0.44岁，男孩占53.1%）完成验光及问卷填写。近视41例）。在按眼别构建的logistic回归（logistic regression）模型中，近视的比值比
研究结论：本队列中近视与睡眠紊乱均较为常见，但未发现二者存在明确相关性的可靠证据。
试验注册：clinicaltrials.gov NCT00848900