Dataset of a study on RDTs for Trypanosoma cruzi infection in Argentina

The file Chagas RDTs_Data Base.cvs contains all the variables used in the analysis of the manuscript “Rapid diagnostic tests for Trypanosoma cruzi infection: field evaluation of two registered kits in endemic and non-endemic regions of Argentina”. This was a prospective intervention study during 2018 to evaluate two registered RDTs for Chagas Disease (infection by T. cruzi), in Argentina (Salta province and Buenos Aires city). The study recruited 607 volunteers older than 18 years and performed the Ab Standard Diagnostics SD Bioline® (SD) and WL Check Chagas Wiener Lab® (WL) RDTs in situ with whole blood samples, and then performed confirmatory serology at a reference center. The data set is structured with one record per each participant recluted in the study. Each of the 706 participants was assigned an ID, which is the first variable included in the data set, and subsequently variables on participant’s information for eligibility criteria, results of RDTs and conventional serological tests and others variables created from the previous ones. From recruited participants, 545 cases fulfilled the criteria for accuracy analysis of SD and WL RDTs. The analysis of this data set was done with Stata version 11.2, and some complementary analysis in EpiDat version 3.1.

文件"Chagas RDTs_Data Base.cvs"包含了论文《克氏锥虫（Trypanosoma cruzi）感染的快速诊断检测：阿根廷流行与非流行区域两款注册试剂盒的现场评估》分析所用的全部变量。本研究为2018年开展的前瞻性干预研究，旨在评估阿根廷萨尔塔省与布宜诺斯艾利斯市两款针对恰加斯病（克氏锥虫感染）的注册快速诊断检测（Rapid Diagnostic Tests，以下简称RDTs）试剂盒。本研究共招募607名18岁以上志愿者，采用全血样本现场开展Ab Standard Diagnostics SD Bioline®（简称SD）与WL Check Chagas Wiener Lab®（简称WL）两款RDTs检测，随后在参考中心进行确证血清学试验。本数据集以研究纳入的每名参与者为单位构建单条记录，706名参与者每人均分配有唯一识别码（ID），该ID为数据集中的首个变量；后续变量涵盖参与者入组资格相关信息、RDTs与常规血清学试验结果，以及由前述变量衍生得到的其他变量。在招募的参与者中，共有545例符合SD与WL两款RDTs的准确性分析纳入标准。本数据集的分析采用Stata 11.2版本完成，部分补充分析则使用EpiDat 3.1版本进行。