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Characterization of the p53 cistrome - DNA binding cooperativity dissects p53's tumor suppressor functions

ChEBI2014-02-14 更新2026-07-21 收录

p53转录调控

肿瘤抑制基因

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-1394 数据链接链接失效反馈

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资源简介：

Characterization of the p53 cistrome - DNA binding cooperativity dissects p53's tumor suppressor functions

应用场景：

创建时间：

2014-02-14

p53转录调控

肝细胞癌诊断

Table S1. Clinical features of HCC patients. The patients were categorized according to their sex, age, tumour size, differentiation status, tumour stage, HBV infection and cirrhosis and fibrosis stat

NIAID Data Ecosystem70

Cross-validated CE for DiffMut and LOTUS prediction of disease specific TSGs in the single- and multitask settings.

肿瘤抑制基因

多任务学习

Cross-validated CE for DiffMut and LOTUS prediction of disease specific TSGs in the single- and multitask settings.

NIAID Data Ecosystem40

WTX overexpression effect on gastric cell line

癌症分子机制

肿瘤抑制基因

We used microarrays to detail the global gene expression in AGS gastric cancer cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Results provide insight into roles fo

NIAID Data Ecosystem30

Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer

癌症基因组数据

肿瘤抑制基因

The aim of this study is to establish an integrative profiling of recurrent UPDs/UPPs, CNAs and genome-wide methylation status in sporadic CRC. Our results indicate that regions showing high frequenci

NIAID Data Ecosystem60

Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq). Homo sapiens

p53转录调控

PRO-seq/GRO-seq技术

GRO-seq of HCT116 cells treated with Nutlin to activate p53 Overall design: HCT116 cells were treated with Nutlin or DMSO for 1 hour

NIAID Data Ecosystem40