Clinical and demographic characteristics of included subjects.

FTD: Frontotemporal dementia; FTD-GRN+: FTD patients carrying Granulin Thr272fs mutation; aGRN+:asymptomatic subjects carrying Granulin Thr272fs mutation; FTD-CDR: Frontotemporal Dementia modified Clinical Dementia Rating scale. * T-test comparison aGRN+ vs. young healthy controls pClinical and demographic characteristics of included subjects.

FTD：额颞叶痴呆（Frontotemporal dementia）；FTD-GRN+：携带颗粒蛋白（Granulin）Thr272fs突变的额颞叶痴呆患者；aGRN+：携带颗粒蛋白Thr272fs突变的无症状受试者；FTD-CDR：额颞叶痴呆改良版临床痴呆评定量表（Frontotemporal Dementia modified Clinical Dementia Rating scale）。* 针对纳入受试者的临床与人口学特征，开展aGRN+与青年健康对照的t检验比较。