Affymetrix SNP array data for Chronic Lymphocytic Leukemia_diagnostic sample_patient samples. Homo sapiens

High-resolution genomic microarrays provides simultaneous detection of copy-number aberrations such as the known recurrent aberrations in Chronic Lymphocytic Leukemia_diagnostic sample_patient (del(11q), del(13q), del(17p) and trisomy 12), and copy-number neutral loss of heterozygosity. We screened 369 newly diagnosed Chronic Lymphocytic Leukemia_diagnostic sample_patient patient samples from a population-based cohort using 250K single nucleotide polymorphism-arrays. Overall design: Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from peripheral blood samples.

高分辨率基因组微阵列（high-resolution genomic microarrays）可同时检测拷贝数变异（copy-number aberrations），包括慢性淋巴细胞白血病（Chronic Lymphocytic Leukemia）诊断样本中已知的复发性遗传学异常，如del(11q)、del(13q)、del(17p)以及12号染色体三体，同时还可检测拷贝数中性杂合性缺失。本研究使用250K单核苷酸多态性微阵列（250K single nucleotide polymorphism-arrays），对一项基于人群的队列中的369例新确诊慢性淋巴细胞白血病患者的诊断样本开展了筛查。实验整体设计：按照生产商的操作指南，对从外周血样本中提取的DNA进行Affymetrix SNP阵列检测。