Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

Single-cell transcriptome profiling using a 3' droplet-based platform (Chromium,10x Genomics) of CD11b+ cells isolated from the spleen of control and tumor-bearing mice, treated or not with IFN gene therapy.

本数据集采用基于3'端液滴的测序平台（Chromium，10x Genomics），对从对照组与荷瘤小鼠脾脏中分离得到的、经或未经干扰素（IFN）基因治疗处理的CD11b阳性细胞（CD11b+）进行单细胞转录组谱分析。