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In vivo oncogenomics screen identifies novel ependymoma oncogenes and tumor suppressor genes within large chromosomal alterations

ChEBI2015-04-28 更新2026-07-21 收录

室管膜瘤分子机制

肿瘤基因组学筛选

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67497 数据链接链接失效反馈

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In vivo oncogenomics screen identifies novel ependymoma oncogenes and tumor suppressor genes within large chromosomal alterations

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创建时间：

2015-04-28

室管膜瘤分子机制

融合功能分析

Additional file 12: Table S4. (A) Dysregulated pathways driven by RELAFUS1target genes in TSS±10kb in 293T-RELAFUS1 cells. (B) Dysregulated pathways driven by RELAFUS1 target genes in TSS ±10kb in H12

Figshare2021-05-18 更新50

Pro-Inflammatory Cytokines Mediate the Epithelial-to-Mesenchymal-Like Transition of Pediatric Posterior Fossa Ependymoma (single-nucleus RNA-seq)

室管膜瘤分子机制

上皮-间质转化调控

Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is due to limited knowledge about ependymoma tumori

NIAID Data Ecosystem40

Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma

室管膜瘤分子机制

自噬调控通路

Children with ependymoma have high mortality rates because ependymoma is resistant to conventional therapy. Genomic and transcriptomic studies have identified potential targets as significantly altere

NIAID Data Ecosystem20

Additional file 11 of C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation

室管膜瘤分子机制

融合基因调控网络

Additional file 11: Table S3. (A) List of top 10 RELAFUS1 motifs in RELAFUS1 peaks in 293T-RELAFUS1 cells. (B) List of top 5 Rela motifs in Rela peaks in MEFs (C) List of DNA sequences identified as t

Figshare2021-05-18 更新50

Phase separation of YAP fusion proteins drives supratentorial ependymoma (methyl-seq)

室管膜瘤分子机制

YAP融合蛋白相分离

HIPPO-YAP/TAZ signaling has been implicated in supratentorial ependymoma formation from neural progenitor cells (NPC) in the brain, however, the underlying mechanisms to trigger the neural progenitor

NIAID Data Ecosystem30

In vivo oncogenomics screen identifies novel ependymoma oncogenes and tumor suppressor genes within large chromosomal alterations

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