Figure_3_S1_Group_5-A

The purpose of this experiment was to assess the effects of knockout of different J Domain Proteins (JDPs) on tau seeding in tau biosensor cells. JDPs were tested in batches of 8, with each batch including the Non-Targeting control as a negative control and the DnaJC7 KO as a positive control. Each batch of JDPs was tested in biological duplicates (Groups A and B) and each condition was tested in technical triplicates.

本实验旨在评估不同J结构域蛋白（J Domain Proteins, JDPs）的基因敲除对tau生物传感器细胞中tau种子形成的影响。实验以8个为一组的批次开展JDPs测试，每一批次均设置非靶向对照作为阴性对照，并以DnaJC7基因敲除（DnaJC7 KO）作为阳性对照。每一批次的JDPs均设置生物学重复（分为A组与B组），且每种实验条件均进行3次技术重复。