Zoom (ROI-07) at 6.54um of the brain of donor LADAF-2021-17, scanned at ESRF on beamline BM18.

Zoom (ROI-07) at 6.54um of the brain of donor LADAF-2021-17, scanned at ESRF on beamline BM18 using the HiP-CT imaging technique. Hierarchical Phase-Contrast Tomography (HiP-CT) is an X-ray technique that decouples field of view and resolution to image anywhere in the human body with cellular (micron) resolution. Imaging areas can be full organs at a resolution of 25 micron or zoomed regions in these organs with resolutions between 6 and 0.6 micron, one hundred times the resolution of medical CT.

捐赠者LADAF-2021-17的脑部样本，在欧洲同步辐射光源（ESRF）的BM18光束线采用分层相衬断层扫描（Hierarchical Phase-Contrast Tomography，HiP-CT）技术完成扫描，得到了该样本感兴趣区域（Region of Interest，ROI）-07、分辨率为6.54微米的放大成像结果。分层相衬断层扫描（HiP-CT）是一类X射线成像技术，可实现视场与分辨率解耦，从而以微米级细胞分辨率对人体任意部位开展成像。该技术的成像范围可覆盖两类场景：一是以25微米的分辨率对完整器官进行成像，二是对器官局部区域进行放大成像，分辨率区间为6至0.6微米，其分辨率可达医用CT的百倍。