Gene epxression profiling in murine lymphoid-primed multipotent progenitor (LMPP) subpopulations. Gene epxression profiling in murine lymphoid-primed multipotent progenitor (LMPP) subpopulations

To understand the mechanism underlying early DC specification Overall design: LMPP subpopulations were isolated from IRF8-GFP knockin mice

为阐明早期树突状细胞（Dendritic Cell, DC）特化的潜在机制，实验整体设计：从干扰素调节因子8（Interferon Regulatory Factor 8, IRF8）-绿色荧光蛋白（Green Fluorescent Protein, GFP）敲入小鼠中分离得到淋巴样倾向多能祖细胞（Lymphoid-primed multipotential progenitor, LMPP）亚群。