five

These data represent the 2282 commercial clinical samples that were used in the initial study discovery.

收藏
NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://figshare.com/articles/dataset/These_data_represent_the_2282_commercial_clinical_samples_that_were_used_in_the_initial_study_discovery_/13631474
下载链接
链接失效反馈
官方服务:
资源简介:
These samples were collected between October 2014 and October 2016 and were genotyped based on ethnicity (77 for Cau; 75 for AA; 71 for His). The original commercial model incorporated the Gail model +PRS (for which 5 year and lifetime risk score can be found in column O and P; calculated per Dite, 2016). The Gail model risk scores alone can be found in columns M and N. The Streamlined model plus PRS risk scores are in columns Q and R. The polygenic risk scores are in column L were calculated per Mealiffe 2010. The clinical Gail model questions can be found in columns D-K, respectively: current age; age at menarche, age at 1st live birth; previous biopsy; number of previous biopsies; confirmed atypical hyperplasia; ethnicity. (XLSX)

本数据集的样本采集于2014年10月至2016年10月期间,依据种族进行基因分型:高加索人(Caucasian, Cau)77例、非裔美国人(African American, AA)75例、西班牙裔(Hispanic, His)71例。 原始商用模型整合了Gail模型(Gail model)与多基因风险评分(Polygenic Risk Score, PRS),其中5年风险评分与终生风险评分可于O、P列查询,该评分依据Dite等人2016年的研究方法计算得到。 仅使用Gail模型计算的风险评分可见于M、N列。 精简模型结合多基因风险评分的结果位于Q、R列。 列L中的多基因风险评分依据Mealiffe 2010年的研究方法计算得到。 临床Gail模型相关调研问题依次分布于D至K列,分别为:当前年龄、月经初潮年龄、首胎活产年龄、既往乳腺活检史、既往活检次数、确诊不典型增生、种族。 (XLSX)
创建时间:
2021-01-22
二维码
社区交流群
二维码
科研交流群
商业服务