Molecular profiling of ADAM12+ MSCs in B16-OVA melanomas

This study investigates the transcriptome of ADAM12+ mesenchymal stromal cells (MSCs) in B16-OVA (MO5) melanomas RNA sequencing was performed on ADAM12+ (GFP+) and ADAM12- (GFP-) stromal cells isolated from MO5 melanoma in ADAM12-GFP mice

本研究探究了B16-OVA（MO5）黑色素瘤中ADAM12阳性的间充质基质细胞（mesenchymal stromal cells, MSCs）的转录组；研究人员对从ADAM12-GFP小鼠的MO5黑色素瘤中分离得到的ADAM12阳性（绿色荧光蛋白（Green Fluorescent Protein, GFP）阳性）与ADAM12阴性（GFP阴性）的基质细胞进行了RNA测序（RNA sequencing）。