Female MRL/lpr and Non-Obese Diabetic (NOD) Mice Treated with Placebo or Testosterone.

The Influence of Testosterone on Lacrimal Gland Gene Expression in Female Mice of the MRL/lpr and Non-obese Diabetic Models of SjšgrenÕs Syndrome Keywords: Placebo versus Testosterone Treatment. Female placebo and testosterone treated lacrimal glands were harvested from each mouse strain . Tissues were pooled into 3 biological replicates and were hybridized to separate microarrays. Each cRNA prep was hybridized to a GE Healthcare/Amersham Biosciences CodeLink UniSet Mouse 20K I Bioarray and a Affymetrix GeneChip Mouse Expression Array 430A.

本数据集探究睾酮对干燥综合征(Sjögren's Syndrome)MRL/lpr与非肥胖糖尿病模型雌性小鼠泪腺基因表达的影响。关键词：安慰剂与睾酮治疗对照。从上述两种小鼠品系中分别采集经安慰剂处理和睾酮处理的雌性小鼠泪腺组织。将组织混合为3份生物学重复样本，并分别与独立的微阵列（microarray）进行杂交。每份cRNA制备物（cRNA prep）均分别与通用电气医疗集团（GE Healthcare）/安玛西亚生物科学（Amersham Biosciences）的CodeLink UniSet Mouse 20K I生物芯片，以及Affymetrix GeneChip Mouse Expression Array 430A小鼠基因表达芯片进行杂交。