Cdk8, Cyclin C, Med12 or Med13 depletion effect on gene expression in Drosophila S2 cells

Expression profiling following depletion of Mediator Cdk8 module subunits Cdk8, Cyclin C (CycC), Med12 and Med13 72 hours after dsRNA treatment of Drosophila melanogaster S2 cells. Results provide insight into the role of individual Cdk8 module subunits in regulation of transcription. 22 samples. 2 Cdk8 dsRNA, 4 CycC dsRNA, 4 Med12 dsRNA, 4 Med13 dsRNA, 8 control samples including 4 Luciferase (Luc) dsRNA and 4 GFP dsRNA

本数据集源自对黑腹果蝇（Drosophila melanogaster）S2细胞进行双链RNA（dsRNA）处理72小时后，敲低中介体Cdk8模块（Mediator Cdk8 module）各亚基（Cdk8、细胞周期蛋白C（Cyclin C, CycC）、Med12及Med13）的表达谱分析。该数据集结果可揭示Cdk8模块各亚基在转录调控过程中的功能角色。本数据集共计22个样本：其中2个为Cdk8 dsRNA处理组、4个为CycC dsRNA处理组、4个为Med12 dsRNA处理组、4个为Med13 dsRNA处理组，剩余8个为对照组样本，包含4个荧光素酶（Luciferase, Luc）dsRNA处理组与4个绿色荧光蛋白（GFP）dsRNA处理组。