Metabolic syndrome and sexual function in postmenopausal women

ABSTRACT Objective The purpose of this study was to evaluate whether female sexual dysfunction (FSD) is associated with metabolic syndrome (MS) and to identify factors that contribute to FSD in postmenopausal women. Subjects and methods This was a cross-sectional study in 111 sexually active women aged 45-65 years. We applied the Female Sexual Function Index (FSFI) to evaluate the participant’s sexual function and a structured questionnaire to collect demographic, socioeconomic, clinical, anthropometric, and laboratory data. Results The prevalences of MS and FSD were 68.5% and 70.3%, respectively. After logistic regression analysis, we identified the following variables associated with FSD: married status (prevalence ratio [PR] 1.69, 95% confidence interval [95% CI] 1.16-2.47, p < 0.01), 6-10 years elapsed since menopause (PR 1.60, 95% CI 1.22-2.09, p < 0.01), occurrence of climacteric symptoms (PR 1.01, 95% CI 1.00-1.02, p = 0.03), and history of sexual abuse (PR 1.40, 95% CI 1.12-1.73, p < 0.01). Conclusion We found a high prevalence of MS and FSD, but no association between both. Married status, time elapsed since menopause, climacteric symptoms, and history of sexual abuse emerged as factors associated with FSD on multivariate analysis.

摘要
研究目的：本研究旨在评估女性性功能障碍（female sexual dysfunction, FSD）是否与代谢综合征（metabolic syndrome, MS）相关，并明确绝经后女性罹患FSD的相关影响因素。

研究对象与方法：本研究为一项横断面研究，共纳入111名年龄介于45~65岁的性活跃女性。采用女性性功能指数（Female Sexual Function Index, FSFI）评估受试者的性功能状态，并通过结构化问卷收集受试者的人口统计学特征、社会经济状况、临床资料、人体测量学指标及实验室检测数据。

研究结果：代谢综合征与女性性功能障碍的患病率分别为68.5%与70.3%。经logistic回归分析后，本研究确定了与FSD显著相关的多项变量：已婚状态（患病率比[PR] 1.69，95%置信区间[95% CI] 1.16~2.47，p < 0.01）、绝经后时长6~10年（PR 1.60，95% CI 1.22~2.09，p < 0.01）、存在更年期症状（PR 1.01，95% CI 1.00~1.02，p = 0.03）以及有性虐待史（PR 1.40，95% CI 1.12~1.73，p < 0.01）。

研究结论：本研究发现代谢综合征与FSD的患病率均处于较高水平，但二者之间未发现显著关联。经多因素分析显示，已婚状态、绝经后时长、更年期症状及性虐待史为绝经后女性发生FSD的相关影响因素。