Effect of trans-vaccenic acid(TVA) treatment on gene expression of mouse CD8+ T cells

To investigate the TVA's effect on mouse CD8+ T cells in vitro, we treated activated mouse CD8+ T cells with DMSO or 20 µM TVA for 24 hours. We then performed gene expression profiling analysis using data obtained from RNA-seq. Comparative gene expression profiling analysis of RNA-seq data for mouse CD8+ T cells treated with DMSO or 20 µM TVA.

为探究TVA对体外培养的小鼠CD8+ T细胞的影响，我们将活化后的小鼠CD8+ T细胞分别用二甲基亚砜（Dimethyl sulfoxide, DMSO）或20 µM的TVA处理24小时。随后采用RNA-seq（RNA测序）获得的数据进行基因表达谱分析。本研究针对经DMSO或20 µM TVA处理的小鼠CD8+ T细胞的RNA-seq数据，实施了对比基因表达谱分析。