DNA methylation data from 11 periodontitis cases and 12 age-matched healthy individuals

Microarray methylation (Infinium® HumanMethylation450 BeadChip from Illumina) was performed on gingival tissue samples from 11 periodontitis cases and 12 age-matched healthy individuals. Bisulphite converted DNA from the 23 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip

本研究针对11例牙周炎病例与12例年龄匹配的健康个体的牙龈组织样本，开展了微阵列甲基化分析（Microarray methylation），所用实验平台为Illumina公司的Infinium® HumanMethylation450 BeadChip芯片。随后，将23份样本经亚硫酸氢盐（Bisulphite）转化得到的DNA，与Illumina Infinium 450k人类甲基化微珠芯片进行杂交。