Prevalence of TB infection and incidence of conversions using TST.
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†6-month prevalence defined as a positive TST result, at either baseline and/or follow-up. 254 children had TST testing at baseline. Among the 16 children without baseline TST testing, 9 had follow up testing; 263 children had a TST performed at either baseline or follow-up. 6 month TST testing was performed on 127 children who had baseline negative TST results and were included in analysis of conversions (includes 9 children without baseline TST results). 74 children were lost to follow-up.
††p values compare rate of baseline positivity to follow-up.
*14 children had baseline TST induration between 5 mm and 10 mm and were classified as negative using a threshold of TST≥10 mm; these children did not receive follow-up TST per study protocol based on having TST≥5 mm.
°Pair-wise comparisons were made between TST thresholds. 6 month prevalence comparing TST threshold of ≥5 mm to threshold of TST≥10 mm: p<0.001; comparing a threshold of TST increase of ≥10 mm to a threshold of ≥5 mm: p = 0.02; comparing threshold of TST increase of ≥10 mm to absolute threshold of ≥10 mm: p = 0.01.
**Pair-wise comparisons were made between TST thresholds. Conversion rates comparing TST threshold of ≥5 mm (13%) to threshold of TST≥10 mm (10%): p = 0.12; comparing a threshold of ≥5 mm (13%) to a threshold of TST increase of ≥10 mm (8%): p = 0.02; comparing threshold of TST increase of ≥10 mm (8%) to absolute threshold of ≥10 mm(10%): p = 0.25.
†6个月患病率定义为基线或随访时结核菌素皮肤试验(Tuberculin Skin Test,TST)结果呈阳性。共计254名儿童在基线阶段接受了TST检测。在16名未行基线TST检测的儿童中,9名完成了随访检测;最终共有263名儿童在基线或随访阶段接受了TST检测。127名基线TST结果阴性且被纳入结核菌素皮肤试验阳转分析的儿童完成了6个月TST检测(其中包含9名无基线TST检测结果的儿童)。另有74名儿童失访。
††p值用于比较基线阳性率与随访阳性率。
*14名儿童的基线TST硬结直径介于5mm至10mm之间,按照TST≥10mm的判定阈值被归类为阴性;根据研究方案,这类TST≥5mm的儿童未接受随访TST检测。
°针对TST阈值开展两两比较:以TST≥5mm阈值与TST≥10mm阈值比较6个月患病率,p<0.001;以TST增幅≥10mm阈值与≥5mm阈值比较,p=0.02;以TST增幅≥10mm阈值与绝对阈值≥10mm比较,p=0.01。
**针对TST阈值开展两两比较:以TST≥5mm阈值(13%)与TST≥10mm阈值(10%)比较阳转率,p=0.12;以TST≥5mm阈值(13%)与TST增幅≥10mm阈值(8%)比较,p=0.02;以TST增幅≥10mm阈值(8%)与绝对阈值≥10mm(10%)比较,p=0.25。
创建时间:
2011-10-31



