Table_1_Waist-to-height ratio and new-onset hypertension in middle-aged and older adult females from 2011 to 2015: A 4-year follow-up retrospective cohort study from the China Health and Retirement Longitudinal Study.docx

BackgroundCentral obesity was closely associated with hypertension. Middle-aged and older adult females, defined as those aged 45 and above, were more likely to suffer from central obesity. For waist-to-height ratio (WHtR) was used as central obesity assessment, the object of this study was to illustrate the relationship between WHtR and the incidence of hypertension in middle-aged and older adult females in China.
MethodsData used in this prospective cohort study was derived from the China Health and Retirement Longitudinal Study (CHARLS) in a baseline survey from 2011 to 2012 with a follow-up duration of 4 years. The waist-to-height ratio was calculated as waist circumstance divided by height, and the cohort was divided into different groups based on WHtR level. The outcome variable was new-onset hypertension.
ResultsOf the 2,438 participants included in the study, 1,821 (74.7%) had high WHtR levels (WHtR ≥ 0.5). As WHtR was closely related to new-onset hypertension in a multivariable logistics regression mode [OR: 7.89 (95% CI: 2.10–29.67)], individuals with high WHtR were also more likely to suffer from hypertension compared with low WHtR levels [OR: 1.34 (95% CI: 1.06–1.69)].
ConclusionWHtR is positively related to the risk of hypertension incidents among middle-aged and older adult females. Individuals with WHtR ≥ 0.5 were more likely to suffer from hypertension.

研究背景：中心性肥胖与高血压密切相关。中年及以上成年女性（定义为45岁及以上人群）更易罹患中心性肥胖。本研究以腰围身高比（waist-to-height ratio, WHtR）作为中心性肥胖的评估指标，旨在阐明中国中年及以上成年女性的WHtR水平与高血压发病风险之间的关联。
研究方法：本前瞻性队列研究的数据来源于2011至2012年的中国健康与养老追踪调查（China Health and Retirement Longitudinal Study, CHARLS）基线调查，随访时长为4年。腰围身高比的计算方式为腰围除以身高，研究队列根据WHtR水平进行分组。结局变量为新发高血压。
研究结果：本研究纳入的2438名参与者中，1821名（74.7%）WHtR水平升高（WHtR ≥ 0.5）。在多变量logistic回归分析中，WHtR与新发高血压密切相关[OR=7.89，95%CI：2.10~29.67]；与WHtR水平较低的人群相比，WHtR水平升高者罹患高血压的风险更高[OR=1.34，95%CI：1.06~1.69]。
研究结论：中国中年及以上成年女性的WHtR水平与高血压发病风险呈正相关。WHtR ≥ 0.5的人群更易罹患高血压。