Single-cell ATAC of WT thymic IEL precursors (IELp)

To examine the chromatin accessibility of IELp, single cell epigenomic analysis of IELp from control mice (Cd4 Cre–Lrffl/fl) were determined by scATACseq Overall design: IELp from control (Cd4 Cre–Lrffl/fl) mice were sorted and single cell transcriptomic analysis was determined by scATAC

为探究IELp的染色质可及性，本研究通过单细胞ATAC测序（scATACseq）对对照组小鼠（Cd4 Cre–Lrffl/fl）来源的IELp开展单细胞表观基因组分析。实验设计概要：分选得到对照组（Cd4 Cre–Lrffl/fl）小鼠的IELp后，采用scATACseq完成其单细胞转录组分析。