Evaluation of the Infinium Methylation 450K technology

Genome-wide DNA methylation profiling of HCT116 WT, HCT116 DNMT1 and DNMT3B double KO, and breast cancer tumors by next generation Infinium assay Bisulfite converted DNA from 22 samples were hybridized to the Illumina's HumanMethylation450 BeadChip

本数据集针对HCT116野生型、HCT116 DNMT1与DNMT3B双基因敲除细胞系以及乳腺癌肿瘤组织，采用新一代Infinium检测技术开展全基因组DNA甲基化谱分析：将22份样本的亚硫酸氢盐转化DNA与Illumina公司的HumanMethylation450 BeadChip芯片进行杂交。