Landscape of epitopes targeted by T cells in 852 convalescent COVID-19 patients: Meta-analysis, immunoprevalence and web platform. Quadeer et al

Complete list of unique SARS-CoV-2-specific T cell epitope-HLA pairs (n=711) reported to elicit response in blood samples of convalescent COVID-19 patients. This table includes, for each epitope, the associated HLA allele, location within the proteome, genetic conservation in global SARS-CoV-2 sequences (as of 20 April 2021), and the computed response frequency across studies (as reported in Figure 2 of the paper). Number of total subjects tested, number of responding subjects, and response frequency per study for each epitope-HLA pair are also listed. For (n=90) SARS-CoV-2 epitopes having a genetic match with SARS-CoV known epitopes, the IEDB IDs of the corresponding SARS-CoV epitopes as well as the associated HLAs are listed. This list of epitopes is compiled from both published studies and non-peer-reviewed studies available so far only on preprint servers. Results from non-peer-reviewed studies should be interpreted with caution.

已报道可在COVID-19康复患者血液样本中引发反应的、独特的SARS-CoV-2特异性T细胞表位-HLA对（SARS-CoV-2-specific T cell epitope-HLA pair）完整列表（n=711）。该表格针对每个表位包含以下信息：关联的HLA等位基因（HLA allele）、在蛋白质组（proteome）中的位置、全球SARS-CoV-2序列中的遗传保守性（genetic conservation）（截至2021年4月20日），以及跨研究计算的反应频率（response frequency）（如论文图2所示）。表格还列出了每个表位-HLA对在各研究中的总测试受试者数量、应答受试者数量及反应频率。对于与SARS-CoV已知表位存在遗传匹配的90个（n=90）SARS-CoV-2表位，表格列出了对应SARS-CoV表位的IEDB ID（IEDB ID）及关联的HLA。该表位列表综合自已发表研究及目前仅在预印本服务器（preprint server）上可获取的非同行评审研究。对非同行评审研究的结果应谨慎解读。