RNA sequencing of 6 HGSOC and 5 FTE. RNA sequencing of 6 HGSOC and 5 FTE

Ovarian cancer is the most lethal gynecological malignancy. Recurrence and chemoresistance are tough challenges leading to poor prognosis. To further identify key genes in tumor progression, we performed RNAseq for 6 high-grade serous ovarian cancer and 5 fallopian tube and analysis of differentially expressed genes for hub genes selection. Overall design: The assay was performed on 6 HGSOC and 5 FTE for RNA seq.

卵巢癌（Ovarian cancer）是致死率最高的妇科恶性肿瘤。复发与化疗耐药是导致患者预后不良的棘手难题。为进一步明确肿瘤进展过程中的关键基因，我们对6例高级别浆液性卵巢癌（high-grade serous ovarian cancer, HGSOC）样本与5例输卵管上皮（fallopian tube epithelium, FTE）样本开展RNA测序（RNAseq），并通过差异表达基因分析筛选核心基因（hub genes）。实验整体设计：本实验针对6例HGSOC样本与5例FTE样本进行RNA测序。