Directed evolution detects aneuploidy dependent and independent mechanisms conferring resistance to azoles in Candida auris

RNA-seq experiments were performed to identify metabolic pathways that are differentially expressed upon FLC evolved drug resistance replicates as compared to parental replicates.

本研究开展RNA测序（RNA-seq）实验，旨在鉴定经氟康唑（FLC）诱导进化出耐药性的生物学重复样本与亲本生物学重复样本之间差异表达的代谢通路。