Double Challenge: COVID-19 meets the Influenza - First case report in Colombia

Coinfection of SARS-CoV-2 and Influenza virus (Flurona) is rare, a literature search was carried out in the databases PubMed, Scopus, as well as Google Scholar, in Spanish and English, and it was found that no cases have been previously reported in Colombia. Although they have a similar mode of transmission and clinical presentation, there are important differences in treatment. The aggressiveness of the two viruses can cause respiratory failure and death. The case of an 83-year-old male subject with cardiovascular comorbidities is presented, who required management in the intensive care unit for congestive heart failure and severe aortic valve disease, during hospitalization he presented respiratory failure in which Flurona was documented. He received treatment with Oseltamivir, oxygen support and therapeutic thoracentesis. It was decided to perform transcatheter aortic valve implantation (TAVI) and he died during the procedure. In conclusion, the management of patients with Flurona represents a diagnostic and therapeutic challenge, so a multidisciplinary approach is imperative to obtain better clinical results.

严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）与流感病毒（Influenza virus）的合并感染（Flurona）较为罕见。本研究以西班牙语和英语为检索语言，在PubMed、Scopus及Google Scholar数据库中开展文献检索，结果显示此前哥伦比亚尚未有该合并感染病例的报道。尽管二者传播途径与临床表现相似，但在治疗方案上存在显著差异。两种病毒的侵袭性均可引发呼吸衰竭乃至死亡。本文报告1例合并心血管基础疾病的83岁男性患者：该患者因充血性心力衰竭与重度主动脉瓣疾病需入住重症监护室治疗，住院期间出现呼吸衰竭，经检测确诊为Flurona合并感染。患者接受了奥司他韦（Oseltamivir）治疗、氧支持疗法及治疗性胸腔穿刺术。临床团队决定为其实施经导管主动脉瓣植入术（transcatheter aortic valve implantation, TAVI），但患者在手术过程中死亡。综上，Flurona合并感染患者的诊疗工作兼具诊断与治疗挑战，因此亟需采用多学科协作模式以获得更优的临床结局。