Data Sheet 1_Global research trends in surgical management of choledochal cysts: a bibliometric analysis from 2000 to 2024.docx

IntroductionCholedochal cysts (CCs), which are congenital biliary anomalies prevalent in Asia, predominantly affect children and carry the risk of severe complications, including malignancy. Surgical intervention, evolving from open to minimally invasive (laparoscopic/robotic) techniques, remains the cornerstone of management. Despite growing research, no bibliometric analysis has mapped the global trends in CCs surgical studies. The aim of this study was to comprehensively analyze the advances in the surgical treatment of CCs since the 21st century and to predict future research directions.
MethodsUsing the Web of Science Core Collection (2000–2024), we analyzed 1,064 publications on CCs surgery via Bibliometrix and CiteSpace. The search terms included surgical techniques (e.g., “laparoscop*,” “Roux-en-Y”) and disease terms (e.g., “choledochal cyst*”). The data encompassed authorship, citations, institutions, and keywords.
ResultsAverage Annual publications increased by 5.95%, peaking by 2023 (n = 93). China (n = 579) and Japan (n = 398) dominated the research output, yet international collaboration was limited (MCP rate <10%). High-impact studies emphasized long-term malignancy risks after Roux-en-Y anastomosis and laparoscopic superiority over open surgery. Keyword analysis revealed shifting foci: “management” (n = 241) and “children” (n = 204) were predominant, while “robotic surgery” emerged post-2010. Institutions such as Monash University and the Capital Institute of Pediatrics led productivity, with the Journal of Pediatric Surgery being the top publisher.
ConclusionSurging research on CCs surgery highlights evolving priorities: bibliometrics reveal a growing focus on long-term outcomes and minimally invasive techniques (laparoscopic/robotic). Enhanced preoperative and postoperative management and novel diagnostic methods are critical. Global collaboration and standardized training remain pivotal for optimizing patient prognosis.

引言
胆总管囊肿（Choledochal cysts，CCs）是一类高发于亚洲的先天性胆道畸形，主要累及儿童群体，且存在包括恶性病变在内的严重并发症风险。手术治疗始终是该疾病的核心管理手段，其技术路径已从传统开放手术逐步演进至微创（腹腔镜/机器人）手术范畴。尽管该领域的研究规模持续扩大，但目前尚无文献计量分析对胆总管囊肿外科研究的全球发展趋势进行系统梳理。本研究旨在全面分析21世纪以来胆总管囊肿外科治疗的研究进展，并预测未来的研究方向。

材料与方法
本研究依托Web of Science核心合集（2000–2024年）数据库，通过Bibliometrix与CiteSpace两款文献计量工具，对1064篇胆总管囊肿外科相关文献进行分析。检索词涵盖手术技术类（如"laparoscop*"、"Roux-en-Y"）及疾病相关术语（如"choledochal cyst*"）。分析维度包括作者贡献、被引频次、研究机构及关键词分布。

结果
年平均发文量以5.95%的速率增长，于2023年达到峰值（共93篇）。中国（579篇）与日本（398篇）为该领域的核心发文国家，但国际合作程度较低（多国合作发文率<10%）。高影响力研究重点关注Roux-en-Y吻合术后的远期恶性病变风险，以及腹腔镜手术相较于开放手术的临床优势。关键词分析显示研究热点持续变迁："诊疗管理"（241篇）与"儿童"（204篇）为高频研究主题，而"机器人手术（robotic surgery）"自2010年后逐渐成为新兴研究方向。莫纳什大学与首都儿科研究所为该领域的核心高产研究机构，《Journal of Pediatric Surgery（小儿外科杂志）》为该领域最高产的学术刊载期刊。

结论
胆总管囊肿外科领域的研究热度持续攀升，反映出该领域研究重点的演变：文献计量分析显示，当前研究愈发聚焦于远期预后与微创技术（腹腔镜/机器人手术）。优化围手术期管理与创新诊断方法仍是该领域的关键发展方向。加强国际学术合作与规范化培训，对于改善患者预后仍具有核心意义。