Pneumonia Due to Bordetella bronchiseptica in a Cystic Fibrosis Patient: 16S rRNA Sequencing for Diagnosis Confirmation

Bordetella bronchiseptica was identified as an unusual etiologic agent of pulmonary recurrent exacerbations and pneumonia in a cystic fibrosis (CF) patient by utilizing a 16S rRNA molecular kit in our hospital's clinical laboratory. This method appears to be a useful approach for identifying new emerging CF pathogens when discrepancies exist between phenotypical tests.

本院检验科采用16S rRNA分子检测试剂盒（16S rRNA molecular kit），在1例囊性纤维化（CF）患者体内检出支气管败血波氏杆菌（Bordetella bronchiseptica），该菌为引发肺部反复急性加重与肺炎的罕见致病病原体。当表型检测（phenotypical tests）结果存在偏差时，此种检测方法可作为识别新型囊性纤维化相关致病菌的有效手段。