Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

ChEBI2010-05-22 更新2026-07-21 收录

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DNA复制起始位点

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-15082 数据链接链接失效反馈

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Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

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2010-05-22

Table S1 from Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer

癌症靶向治疗

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Disruption of the enzymatic activities of the transcription factor TFIIH by the small molecules Triptolide (TPL) or THZ1 could be used against cancer. Here, we used the MCF10A-ErSrc oncogenesis model

Figshare2020-06-01 更新50

Co-regulated gene expression downstream of a single transcription factor controls the acquisition of corticospinal motor neuron identity

神经元亚型

转录调控机制

The neocortex contains an unparalleled diversity of neuronal subtypes responsible for complex behavior. Each cortical neuron has distinct traits, which are developmentally acquired under the control o

NIAID Data Ecosystem40

The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Promotes H2B Ubiquitylation Through a Direct Interaction with the Ubiquitin Conjugase Rad6

组蛋白H2B泛素化

转录调控机制

Transcription by RNA polymerase II is regulated by epigenetic modifications to the chromatin template. The mono-ubiquitylation of H2B is established during transcription elongation and broadly impacts

NIAID Data Ecosystem10

Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding [RNA-Seq]

染色质三维构象调控

转录调控机制

Establishment of cell lineage specification, maintenance of cellular states and cellular responses to developmental cues rely on gene regulation and spatial genome organization during early developmen

NIAID Data Ecosystem50

Dual regulation of open-complex formation and promoter clearance by Arc explains a novel repressor to activator switch.

转录调控机制

基因表达

In studies of variants of the P(ant) promoter of bacteriophage P22, the Arc protein was found not only to slow the rate at which RNA polymerase forms open complexes but also to accelerate the rate at

PubMed Central1996-08-20 更新30

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

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