Supporting data for "Development of inhaled powder formulation of antimicrobial agents by spray freeze drying technology"

The dataset include raw data and summarised data for the research projects of developing inhalable dry powder formulations of antimicrobial agents. The raw data were obtained from the in evaluation of physicochemical characterisation (particle size, morphology, dissolution, differential scanning calorimetry, powder X-ray diffraction, etc.) and aerosol performance, and <i>in vivo</i> studies that investigate the biodistribution, pharmacokinetics, and antimicrobial activity of the formulated powder formulations. In this dataset, two antimicrobial agents, voriconazole and tamibarotene, were investigated.

该数据集涵盖抗菌剂可吸入干粉制剂研发项目的原始数据与汇总数据。原始数据源自理化特性表征（physicochemical characterisation，包括粒径、形态、溶出度、差示扫描量热法、粉末X射线衍射等）及气溶胶性能的评估，以及探究制剂粉末生物分布、药代动力学与抗菌活性的<i>体内</i>（in vivo）研究。本数据集中对两种抗菌剂——伏立康唑与他米巴罗汀进行了研究。