Additional file 3: of Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

Figure S2. Phylogenetic tree of HHV-6B complete U90/91 and U94/100 loci. HHV-6B genomes were aligned using MAFFT, curated for sequence outside of repeat regions, and phylogenetic trees were constructed using MrBayes along the 6 kb U90/91 (A), and 10 kb U94-100 (B) regions. HHV6-6B NY310 was used as an outgroup. Samples are colored and labeled for origin based on New York (green), Japan (blue), or iciHHV6-B from HSCT recipients or their donors in Seattle (black), as well as whether two genomes were recovered from first-degree relatives (red). Location images purchased from Adobe Stock. (ZIP 656 kb)

图S2。人类疱疹病毒6B型（HHV-6B）完整U90/91与U94/100基因座的系统发育树。
本研究使用MAFFT对HHV-6B基因组进行序列比对，对重复区域以外的序列进行整理筛选，并分别针对6 kb的U90/91区域（图A）与10 kb的U94-100区域（图B），通过MrBayes构建系统发育树。
以HHV-6B NY310作为外类群。
样本按来源进行配色与标注：来自纽约的样本为绿色，来自日本的样本为蓝色，来自西雅图造血干细胞移植（Hematopoietic Stem Cell Transplantation, HSCT）受者或其供者的整合型HHV-6B（iciHHV-6B）样本为黑色；此外，从一级亲属体内分离得到的两株基因组样本标记为红色。
本图所用的位置图像购自Adobe Stock图库。
（ZIP 656 KB）