RNA helicase DDX21 mediates nucleotide stress responses (ChIP-Seq)

The RNA helicase DDX21 acts as trancriptional sensor for nucleotide lowering ChIP-seq analysis of DDX21 and CDK9 in human A375 melanoma cells treated with DMSO, 25 uMA77 1726 and 25uM A771726 plus nucleotides

RNA解旋酶（RNA helicase）DDX21可作为核苷酸降低过程的转录传感器；本数据集针对经二甲基亚砜（DMSO）、25μM A771726以及25μM A771726联合核苷酸处理的人A375黑色素瘤细胞，开展了DDX21与细胞周期蛋白依赖性激酶9（CDK9）的染色质免疫共沉淀测序（ChIP-seq）分析。