Raw data for "The effects of Five-Animal exercise in ankylosing spondylitis: A randomized controlled study"

This dataset contains individual participant data from a parallel‐group randomized controlled trial evaluating the add-on effects of Five-Animal exercise (Wuqinxi) in patients with ankylosing spondylitis. Sixty-four adults were randomly allocated to a Wuqinxi plus usual care group (n = 32) or a usual care only control group (n = 32) and followed for 12 weeks.

The file includes one row per participant and multiple columns for baseline and week-12 measurements. Variables cover sociodemographic characteristics (age, sex, marital status, education, smoking and alcohol use), disease-related factors (disease duration, HLA-B27 status, use of NSAIDs and biologics), clinical and functional outcomes (finger-to-ground distance, occiput-to-wall distance, Modified Modified Schober test, BASFI, BASDAI, BASMI, VAS pain), radiographic scores (mSASSS, SPARCC), serum inflammatory biomarkers (ESR, CRP, IL-10, IL-17) and molecular markers (Act1, IκBα, Smad1, NF-κB/p65), as well as SF-36 domain scores (PF, RP, BP, GH, VT, SF, RE, MH) and selected change scores.

All data are fully de-identified: only study IDs and randomized group labels are provided, with no names, dates of birth, contact details or other direct identifiers. A separate data dictionary file (AS_Wuqinxi_RCT_datadictionary.xlsx) defines all variables, units and coding schemes to facilitate reuse and replication of the analyses reported in the associated article.

本数据集包含一项平行组随机对照试验的个体参与者数据，该试验旨在评估五禽戏（Five-Animal exercise, Wuqinxi）对强直性脊柱炎（ankylosing spondylitis）患者的附加干预效果。本研究共纳入64名成人受试者，按随机原则分配至五禽戏联合常规护理组（n=32）或仅常规护理对照组（n=32），随访时长为12周。

该数据集文件每行对应一名参与者，包含多列基线及第12周的测量指标。变量类别涵盖：社会人口学特征（年龄、性别、婚姻状况、受教育程度、吸烟与饮酒行为）；疾病相关因素（病程、HLA-B27状态、非甾体抗炎药（NSAIDs）及生物制剂使用情况）；临床与功能结局指标（指地距、枕墙距、双改良Schober试验（Modified Modified Schober test）、BASFI、BASDAI、BASMI、疼痛视觉模拟评分（VAS pain））；影像学评分（mSASSS、SPARCC）；血清炎症生物标志物（红细胞沉降率（ESR）、C反应蛋白（CRP）、IL-10、IL-17）与分子标志物（Act1、IκBα、Smad1、NF-κB/p65）；此外还包含SF-36各维度得分（PF、RP、BP、GH、VT、SF、RE、MH）及指定的变化量得分。

所有数据均已完成完全去标识化处理：仅提供研究编号与随机分组标签，未包含姓名、出生日期、联系方式或其他直接识别信息。另有一份独立的数据字典文件（AS_Wuqinxi_RCT_datadictionary.xlsx），对所有变量、测量单位及编码方案进行了定义，以方便后续研究复用该数据集并复现关联论文中报告的分析结果。