The Netherlands BAG

The Netherlands BAG comprises structural biology and enzymology groups at five dutch universities (Utrecht, Groningen, Leiden, Eindhoven and Wageningen) and at the Netherlands Cancer Institute in Amsterdam, with a total of thirteen PIs. The research projects carried out in these groups can be largely classified into two major themes: (i) research on proteins and systems with a strong biomedical relevance and (ii) research concerning the design of new biocatalysts for green chemistry and new-to-nature reactions. Projects deal with prokaryotic and eukaryotic proteins, membrane and soluble proteins, cell surface receptors, and protein-protein, protein-ribonucleotide, protein-drug and enzyme-ligand complexes.

荷兰BAG（The Netherlands BAG）由五所荷兰大学（乌得勒支大学、格罗宁根大学、莱顿大学、埃因霍温大学及瓦赫宁根大学）和阿姆斯特丹的荷兰癌症研究所的结构生物学与酶学研究组组成，共计十三位首席研究员（Principal Investigator，PI）。这些研究组开展的项目大致可分为两大主题：（i）具有强生物医学相关性的蛋白质及系统研究；（ii）面向绿色化学与非天然反应（new-to-nature reaction）的新型生物催化剂（biocatalyst）设计研究。项目涉及原核（prokaryotic）与真核（eukaryotic）蛋白质、膜蛋白（membrane protein）与可溶性蛋白（soluble protein）、细胞表面受体（cell surface receptor），以及蛋白质-蛋白质、蛋白质-核糖核苷酸（protein-ribonucleotide）、蛋白质-药物和酶-配体复合物（enzyme-ligand complex）。