Chromosome conformation for wild type, eco1-aa, cdc6-mn and eco1-aa cdc6-mn strains arrested in meiotic prophase I

High-resolution Hi-C in meiotic prophase I arrested cells Purpose: to determine the relative impact of Eco1 and cohesive cohesin on loop extrusion in meiotic prophase I, with a focus on the pericentromere.

本数据集为减数分裂I前期阻滞细胞的高分辨率Hi-C（High-resolution Hi-C）实验数据，研究目的为明确Eco1与黏合型黏连蛋白（cohesive cohesin）对减数分裂I前期染色质环挤出过程的相对影响，研究重点聚焦于着丝粒周边区域（pericentromere）。