DNA copy number analysis from mice with radiation-induced acute myeloid leukemia

Certain mouse strains such as CBA, C3H and RFM, have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this serie was generated by using spleen DNA from CBA mice which were irraidated with either gamma-rays or heavy ion (HZE) particles. Spleen DNA with radiation-induced AML was compared with DNA from normal CBA mice. Comparison of spleen DNA from CBA mice with radiation-induced AML vs genomic DNA from normal CBA mice

诸如CBA、C3H及RFM在内的多种小鼠品系，其辐射诱导急性髓系白血病（acute myeloid leukemia, AML）的发病率较高。本系列数据集的样本来源于经γ射线或重离子（heavy ion, HZE）粒子照射的CBA小鼠的脾脏DNA。研究将辐射诱导AML的CBA小鼠脾脏DNA与正常CBA小鼠的基因组DNA进行了比对分析。